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If you have systemic sclerosis, prednisolone could cause problems with your kidneys at certain doses, so you might not be able to take this type of steroidfor a while.
How is prednisolone different from corticosteroids?
Prednisolone is a more common steroid used to treat systemic sclerosis. It binds to your lymphoid tissue, blocking the flow of lymph (the fluid that passes through your arms, legs and trunk). The drugs block both a protein called interleukin-6 (IL-6), which triggers inflammation, and a protein called interferon beta-1a (IFN-β). Because IL-6 is a major component of the immune system, treating and managing systemic sclerosis by using corticosteroids could potentially increase your risk of an infection.
However, while prednisolone is taken as a steroid, corticosteroids are taken as a long-term treatment.
Prednisolone can also be used to treat certain conditions that might have led to your MS; such as asthma and cystic fibrosis (a condition in which cysts or cysts become hard or painful).
Some types of prednisolone are prescribed to treat type 1 diabetes, high blood cholesterol, diabetes of a different type, and some types of cancer chemotherapy.
The side effect of using long-term corticosteroids is reduced bone growth (osteoporosis), which means that the bone on which your joints rest will start to look different; especially if you take steroids regularly. These side effects can lead to bone loss that is irreversible, which is why prednisolone can increase your risk of osteoporosis.
What is the long-term risk of using prednisolone?
There is no evidence that prednisolone makes you more likely to develop other conditions that could lead to MS than taking other treatments. But you can’t take prednisolone for a long time without side effects if you want to continue using this medication.
How is prednisolone best taken?
Use a nonsteroidal anti-inflammatory medicine like ibuprofen (Advil) or naproxen (Aleve) as directed by your healthcare provider. (These medicines can block the effects of prednisolone and can sometimes cause side effects.)
After you stop taking prednisolone, you should talk with your healthcare provider about the right time to reintroduce prednisolone to your body. Depending on your disease, timing may be up to 6 months after your last dose, or longer.
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